Beneficial role of phytochemicals on oxidative stress and age-related diseases
| Autor: | Ravirajsinh N. Jadeja, Simone Beninati, Antonio Facchiano, Roberto Nisini, Manuela Bartoli, Francesco Facchiano, Stefano Pieretti, Cinzia Forni, Claudio Tabolacci, Giorgia Valle, Daniela D'Arcangelo, Sandro Norelli |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Aging
Antioxidant medicine.medical_treatment Settore BIO/01 lcsh:Medicine antioxidant activity Endogeny Inflammation Disease Review Article Pharmacology phytochemicals antioxidant activity age related disease medicine.disease_cause General Biochemistry Genetics and Molecular Biology Antioxidants Diabetes mellitus medicine Animals Humans chemistry.chemical_classification Metabolic Syndrome Reactive oxygen species General Immunology and Microbiology business.industry lcsh:R Neurodegenerative Diseases General Medicine medicine.disease phytochemicals Oxidative Stress chemistry age related disease medicine.symptom Metabolic syndrome business Reactive Oxygen Species Oxidative stress |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2019 (2019) |
| Popis: | Aging is related to a number of functional and morphological changes leading to progressive decline of the biological functions of an organism. Reactive Oxygen Species (ROS), released by several endogenous and exogenous processes, may cause important oxidative damage to DNA, proteins, and lipids, leading to important cellular dysfunctions. The imbalance between ROS production and antioxidant defenses brings to oxidative stress conditions and, related to accumulation of ROS, aging-associated diseases. The purpose of this review is to provide an overview of the most relevant data reported in literature on the natural compounds, mainly phytochemicals, with antioxidant activity and their potential protective effects on age-related diseases such as metabolic syndrome, diabetes, cardiovascular disease, cancer, neurodegenerative disease, and chronic inflammation, and possibly lower side effects, when compared to other drugs. |
| Databáze: | OpenAIRE |
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