Risk factors for Charcot foot
| Autor: | Alexandre Magno da Nóbrega Marinho, João Luís da Silva, Priscilla Leite Campelo, Ricardo David Couto, Marta Barreto de Medeiros Nóbrega, Roque Aras, Marcos André Lima Nunes, Eduardo Martins Netto, Víctor Nóbrega Quintas Colares |
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| Jazyk: | angličtina |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism lcsh:Medicine Type 2 diabetes lcsh:Diseases of the endocrine glands. Clinical endocrinology Body Mass Index Diabetic Neuropathies Risk Factors Internal medicine Diabetes mellitus Charcot foot medicine Odds Ratio Humans lcsh:RC648-665 business.industry lcsh:R Case-control study Age Factors Odds ratio Charcot neuroarthropathy Middle Aged medicine.disease Diabetic foot Confidence interval diabetic neuropathy Surgery Diabetes Mellitus Type 2 Socioeconomic Factors Case-Control Studies Multivariate Analysis Female Arthropathy Neurogenic business Body mass index Foot (unit) diabetic foot |
| Zdroj: | Archives of Endocrinology and Metabolism, Vol 59, Iss 3, Pp 226-230 Archives of Endocrinology and Metabolism, Volume: 59, Issue: 3, Pages: 226-230, Published: JUN 2015 Archives of Endocrinology and Metabolism v.59 n.3 2015 Arquivos de Endocrinologia e Metabolismo Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) instacron:SBEM |
| ISSN: | 2359-4292 |
| Popis: | Objective Diabetes mellitus is the main cause of Charcot neuroarthropathy and is clinically classified as follows: Charcot foot, acute Charcot foot (ACF) when there is inflammation, and inactive Charcot foot when inflammatory signs are absent. The aim of this study was to identify the risk factors for ACF in patients with type 2 diabetes mellitus.Materials and methods A matched case-control study was conducted to assess the factors associated with acute Charcot foot from February 2000 until September 2012. Four controls for each case were selected 47 cases of ACF and 188 controls without ACF were included. Cases and controls were matched by year of initialization of treatment. Conditional logistic regression was used to estimate matched odds ratios (ORs) and 95% confidence intervals (95% CIs).Results In multivariate analysis, patients having less than 55 years of age (adjusted OR = 4.10, 95% CI = 1.69 – 9.94), literate education age (adjusted OR = 3.73, 95% CI = 1.40 – 9.92), living alone (adjusted OR = 5.84, 95% CI = 1.49 – 22.86), previous ulceration (adjusted OR = 4.84, 95% CI = 1.62 – 14.51) were at increased risk of ACF. However, peripheral arterial disease (adjusted OR = 0.16, 95% CI = 0.05 – 0.52) of 6.25 (1.92 – 20.0) was a protective factor.Discussion The results suggest that PCA in type 2 diabetes primarily affects patients under 55 who live alone, are literate, and have a prior history of ulcers, and that peripheral arterial disease is a protective factor. Arch Endocrinol Metab. 2015;59(3):226-30 |
| Databáze: | OpenAIRE |
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