Renal problems in black South African children *
| Autor: | Thomson Pd |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Nephrotic Syndrome Takayasu's arteritis Black People Kidney South Africa Membranous nephropathy medicine Humans Rapidly progressive glomerulonephritis Renal Insufficiency Arteritis Child Congenital nephrotic syndrome business.industry Glomerulonephritis medicine.disease Kidney Transplantation Surgery Transplantation Nephrology Pediatrics Perinatology and Child Health Female Kidney Diseases business Nephrotic syndrome |
| Zdroj: | Pediatric Nephrology. 11:508-512 |
| ISSN: | 1432-198X 0931-041X |
| Popis: | Black South African children have an increased prevalence of acute post-streptococcal glomerulonephritis, focal glomerulosclerosis, hepatitis B-associated membranous nephropathy, congenital syphilis, congenital nephrotic syndrome with Alport-like basement membrane changes and Takayasu's arteritis, but a paucity of reflux nephropathy, polycystic kidney disease and non-shigella-induced haemolytic uraemic syndrome. However, in recent years, the haemolytic uraemic syndrome has become more prevalent in black children; this is usually due to Shigella dysenteriae type 1, and could indicate a different emphasis in the pathogenic mechanism. Focal glomerulosclerosis is the commonest reason for renal failure requiring transplantation in black children with rapidly progressive glomerulonephritis (usually streptococcal induced) being second. Transplantation has been somewhat problematic with a scarcity of kidneys at times, many mismatches and poor compliance in the lower socio-economic groups. The association of tuberculosis with focal glomerulosclerosis and Takayasu's arteritis in black South African children is intriguing. The progression of focal glomerulosclerosis is accelerated in those patients with evidence of previous tuberculosis, and in Takayasu's arteritis the association is almost absolute as experienced locally, with the data suggesting an autoimmune reaction. |
| Databáze: | OpenAIRE |
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