Graham Little-Piccardi-Lassueur syndrome associated with androgen insensitivity syndrome (testicular feminization)
| Autor: | A Miranda-Romero, J Vega Gutiérrez, G Martínez García, F Pérez Milán |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Dermatology Keratosis Pilaris Cicatrix Complete androgen insensitivity syndrome Internal medicine Humans Medicine Testicular feminization integumentary system business.industry Alopecia Keratosis Syndrome Androgen-Insensitivity Syndrome medicine.disease Pubic hair Infectious Diseases Endocrinology medicine.anatomical_structure Hair loss Scalp Dermatoses Male pseudohermaphroditism Female Androgen insensitivity syndrome Graham Little Piccardi Lassueur syndrome business |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology. 18:463-466 |
| ISSN: | 1468-3083 0926-9959 |
| DOI: | 10.1111/j.1468-3083.2004.00945.x |
| Popis: | Graham Little-Piccardi-Lassueur syndrome is characterized by the presence of cicatricial alopecia on the scalp, keratosis pilaris in the skin of trunk and extremities, and non-cicatricial hair loss in pubis and axillae. A frequent form of male pseudohermaphroditism is complete androgen insensitivity syndrome (CAIS), also known as testicular feminization syndrome. It refers to genetic males with XY karyotype who, owing to a lack of sensitivity in the peripheral androgenic receptors, develop a female phenotype. Axillary and pubic hair is typically scarce or absent. To our knowledge, this is the first case describing the association of the two processes. The presence of both processes in the same patient furthers our understanding of Graham Little-Piccardi-Lassueur syndrome as it rejects the influence of androgens in the alopecias accompanying this syndrome. The coincidence of non-cicatricial alopecia in axillary and pubic hair in both processes is also remarkable. |
| Databáze: | OpenAIRE |
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