Three initial diets for management of mild acute pancreatitis: a meta-analysis
Autor: | Xiaoliang Zhu, Xun Li, Yumin Li, Wenbo Meng, Wence Zhou |
---|---|
Rok vydání: | 2011 |
Předmět: |
Adult
Male medicine.medical_specialty Liquid diet Databases Factual Brief Article Subgroup analysis Cochrane Library Gastroenterology law.invention Randomized controlled trial law Internal medicine medicine Humans Randomized Controlled Trials as Topic business.industry Disease Management General Medicine Middle Aged medicine.disease Surgery Diet Hospitalization Pancreatitis Relative risk Meta-analysis Acute pancreatitis Female business |
Zdroj: | World journal of gastroenterology. 17(37) |
ISSN: | 2219-2840 |
Popis: | AIM: To compare non-liquid and clear-liquid diets, and to assess whether the latter is the optimal treatment for mild acute pancreatitis. METHODS: The Cochrane Library, PUBMED, EMBASE, EBM review databases, Science Citation Index Expanded, and several Chinese databases were searched up to March 2011. Randomized controlled trials (RCTs) that compared non-liquid with clear-liquid diets in patients with mild acute pancreatitis were included. A meta-analysis was performed using available evidence from RCTs. RESULTS: Three RCTs of adequate quality involving a total of 362 participants were included in the final analysis. Compared to liquid diet, non-liquid diet significantly decreased the length of hospitalization [mean difference (MD): 1.18, 95% CI: 0.82-1.55; P﹤0.00001] and total length of hospitalization (MD: 1.31, 95% CI: 0.45-2.17; P = 0.003). The subgroup analysis showed solid diet was more favorable than clear liquid diet in the length of hospitalization, with a pooled MD being -1.05 (95% CI: -1.43 to -0.66; P﹤0.00001). However, compared with clear liquid diet, both soft and solid diets did not show any significant differences for recurrence of pain after re-feeding, either alone [relative risk (RR): 0.95; 95% CI: 0.51-1.87; P = 0.88] and (RR: 1.22; 95% CI: 0.69-2.16; P = 0.49), respectively, or analyzed together as non-liquid diet (RR: 0.80; 95% CI: 0.47-1.36; P = 0.41). CONCLUSION: The non-liquid soft or solid diet did not increase pain recurrence after re-feeding, compared with the clear-liquid diet. The non-liquid diet reduced hospitalization. |
Databáze: | OpenAIRE |
Externí odkaz: |