Unilateral renal agenesis and abrupt onset diabetes: An unfrequent form of MODY type diabetes
| Autor: | María Soledad Ruiz de Adana, María del Mar Roca-Rodríguez, María Concepción García Calzado, María Carmen Ayala-Ortega, Ana Isabel Jiménez-Millán, Florentino Carral San Laureano |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty medicine.medical_treatment Population Diagnosis Differential Solitary Kidney 03 medical and health sciences 0302 clinical medicine Type diabetes Diabetes mellitus medicine Humans Medical history 030212 general & internal medicine Renal Insufficiency Chronic Family history education Renal agenesis Hepatocyte Nuclear Factor 1-beta education.field_of_study business.industry Insulin medicine.disease Obesity Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 business |
| Zdroj: | Medicina Clínica (English Edition). 152:19-21 |
| ISSN: | 2387-0206 |
| DOI: | 10.1016/j.medcle.2017.12.042 |
| Popis: | Introduction MODY diabetes encompasses heterogeneous group of monogenic forms of diabetes with low prevalence. It is not easily diagnosed because of the increase in obesity and family history of diabetes in the general population. Patients and methods We present a clinical case with cardinal symptoms, diabetes,renal insufficiency with no acidosis and with a family history of diabetes and renal agenesis. Results Distinguishing MODY diabetes from DM1 and DM2 is very important to ensure optimal treatment, and because the risk of complications depends on each genetic defect. A proper diagnosis needs a detailed medical history. Discussion An earlier identification of family members at risk and a correct and individualized treatment could be possible. Many of these patients can be managed successfully in monotherapy without insulin therapy. |
| Databáze: | OpenAIRE |
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