H-InvDB in 2009: extended database and data mining resources for human genes and transcripts
| Autor: | Ryuichi Sakate, Yoshiharu Sato, Chisato Yamasaki, Akihiro Matsuya, Katsuhiko Murakami, Jun-ichi Takeda, Takuya Habara, Fusano Todokoro, Takashi Gojobori, Hajime Nakaoka, Tadashi Imanishi, Akiko Ogura Noda |
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| Rok vydání: | 2009 |
| Předmět: |
DNA
Complementary Relation (database) SOAP computer.internet_protocol Information Storage and Retrieval Biology computer.software_genre Set (abstract data type) Annotation User-Computer Interface Text mining Gene cluster Databases Genetic Genetics Humans RNA Messenger Oligonucleotide Array Sequence Analysis Internet Models Genetic business.industry Genome Human Computational Biology Articles Protein Structure Tertiary Multigene Family Human genome Data mining Web service business Databases Nucleic Acid computer Software |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 |
| Popis: | We report the extended database and data mining resources newly released in the H-Invitational Database (H-InvDB; http://www.h-invitational.jp/). H-InvDB is a comprehensive annotation resource of human genes and transcripts, and consists of two main views and six sub-databases. The latest release of H-InvDB (release 6.2) provides the annotation for 219,765 human transcripts in 43,159 human gene clusters based on human full-length cDNAs and mRNAs. H-InvDB now provides several new annotation features, such as mapping of microarray probes, new gene models, relation to known ncRNAs and information from the Glycogene database. H-InvDB also provides useful data mining resources-'Navigation search', 'H-InvDB Enrichment Analysis Tool (HEAT)' and web service APIs. 'Navigation search' is an extended search system that enables complicated searches by combining 16 different search options. HEAT is a data mining tool for automatically identifying features specific to a given human gene set. HEAT searches for H-InvDB annotations that are significantly enriched in a user-defined gene set, as compared with the entire H-InvDB representative transcripts. H-InvDB now has web service APIs of SOAP and REST to allow the use of H-InvDB data in programs, providing the users extended data accessibility. |
| Databáze: | OpenAIRE |
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