Effects of Estradiol-17/β on Reproduction in Adult Male Rats
| Autor: | Shiva K. Saksena, M. C. Chang, Dorothy M. Hunt |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Time Factors media_common.quotation_subject Population Genitalia Male Biology Andrology Endocrinology Atrophy Internal medicine medicine Animals Testosterone Spermatogenesis education Beta (finance) reproductive and urinary physiology media_common Azoospermia education.field_of_study Dose-Response Relationship Drug Estradiol urogenital system Oligospermia Organ Size Luteinizing Hormone medicine.disease Sperm Rats Hypothalamic pituitary axis Reproduction |
| Zdroj: | Archives of Andrology. 2:129-133 |
| ISSN: | 0148-5016 |
| DOI: | 10.3109/01485017908987304 |
| Popis: | Estradiol-17 beta (E2-17 beta) treatment induced dose-related reduction of sperm population and eventual azoospermia, atrophy of accessory organs, and suppressed serum LH and testosterone levels. In spite of all these alterations mating behavior was not affected, although the number of implantation sites paralleled the reduction of sperm population, suggesting that the primary detectable response to E2-17 beta treatment is related to the steroidogenic components of the testis and the hypothalamic pituitary axis. The duration of treatment is more critical for the induction of azoospermia in the rat than the total dose of E2-17 beta. |
| Databáze: | OpenAIRE |
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