Stereodivergent Synthesis of 1,3-Dienes via Protodeboronation of Homoallenylboronic Esters

Autor:	Ryota Sakamoto, Minami Odagi, Atsuto Izumiseki, Kaname Konuki, Kazuo Nagasawa
Rok vydání:	2022
Předmět:	Organic Chemistry Esters Polyenes Alkenes
Zdroj:	The Journal of Organic Chemistry. 87:8084-8098
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.2c00744
Popis:	Vinylboronic esters and allylboronic esters are well known to afford olefins by protodeboronation, and therefore homoallenylboronic esters should be similarly available as precursors for 1,3-dienes, but this strategy has not been well explored due to the limited availability of homoallenylboronic esters. Here, we describe a versatile synthesis of homoallenylboronic esters via lithiation-borylation and subsequent 1,2-rearrangement. The resulting homoallenylboronic esters were successfully converted into
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0f976403a4256da3d2b4077af21d9e https://doi.org/10.1021/acs.joc.2c00744 Zobrazit plný text záznamu