Drosophila locus with gene-dosage effects on rhodopsin

Autor:	N. J. Scavarda, W. L. Pak, Joseph E. O'Tousa
Rok vydání:	1983
Předmět:	Genetics Opsin Multidisciplinary genetic structures biology Mutant Structural gene Locus (genetics) Compound eye biology.organism_classification Gene dosage Rhodopsin biology.protein sense organs Drosophila melanogaster Biological Sciences: Genetics
Zdroj:	Scopus-Elsevier
ISSN:	1091-6490 0027-8424
DOI:	10.1073/pnas.80.14.4441
Popis:	Mutations that decrease the amplitude of the prolonged depolarizing afterpotential (PDA) in Drosophila melanogaster have been shown to have reduced rhodopsin content in the rhabdomeres of photoreceptor cells. In the present study, a genetic analysis of a class of third chromosome PDA-defective mutants localized the ninaE locus to the salivary band region 92A-B. In flies with only one copy of this region instead of the normal two copies, and in ninaE heterozygotes, the rhodopsin content of the major class of photoreceptors is reduced. Three doses of this region increase the rhodopsin content of these photoreceptors. These characteristics of the ninaE locus are expected of the structural gene encoding the major species of opsin in the Drosophila compound eye.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0b7fb53f7bec95bb385e78471d2f08 https://doi.org/10.1073/pnas.80.14.4441 Zobrazit plný text záznamu