Fast analysis of caffeinated beverages using laser diode thermal desorption mass spectrometry (LDTD-MS/MS)
| Autor: | Virginia Sheldon, Sherri B Turnipseed, Terri Thomas, Joseph M Storey, Michael VanSickle, Wendy C. Andersen, Jack J. Lohne, Mark R. Madson |
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| Rok vydání: | 2019 |
| Předmět: |
Calibration curve
Health Toxicology and Mutagenesis Thermal desorption Toxicology Mass spectrometry Tandem mass spectrometry 01 natural sciences Beverages chemistry.chemical_compound 0404 agricultural biotechnology Tandem Mass Spectrometry Caffeine Desorption Chromatography Atmospheric pressure Lasers 010401 analytical chemistry Public Health Environmental and Occupational Health 04 agricultural and veterinary sciences General Chemistry General Medicine 040401 food science 0104 chemical sciences chemistry Methanol Quantitative analysis (chemistry) Food Analysis Food Science |
| Zdroj: | Food Additives & Contaminants: Part A. 36:1616-1625 |
| ISSN: | 1944-0057 1944-0049 |
| DOI: | 10.1080/19440049.2019.1658904 |
| Popis: | A rapid method for quantitative caffeine analysis in carbonated and non-carbonated beverages and liquid dietary supplement products was developed based on the direct sample introduction technique of laser diode thermal desorption atmospheric pressure chemical ionisation with tandem mass spectrometry (LDTD-MS/MS). Product samples were diluted with a mixture of methanol, water, and d3-caffeine internal standard. Sample aliquots were filtered, spotted on a metal-lined LDTD microtitre plate, dried, and thermally desorbed for subsequent ionisation and analysis by MS/MS analysis. Each sample required a 6 s desorption, and sample-to-sample analysis time of less than 30 s per sample. Caffeine yielded a linear calibration curve over the range 0.5-100 μg mL-1 (R2 > 0.995). Caffeine recoveries from fortified samples ranged from 97% to 107% with 0.998) with the regulatory standard HPLC-UV method (AOAC Official Method 979.08). |
| Databáze: | OpenAIRE |
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