Clinical and mycological characteristics of keratitis caused by Colletotrichum gloeosporioides: A case report and review of literature

Autor: Mohammad Soleimani, Alireza Izadi, Seyed Jamal Hashemi, Aleksandra Barac, Mohssen Gramishoar, Mehdi Aminizadeh, Mohammad Ghahri, Sadegh Khodavaisy, Roshanak Daie Ghazvini, Kazem Ahmadikia, Zohre Abedinifar
Rok vydání: 2021
Předmět:
Zdroj: The Journal of Infection in Developing Countries. 15:301-305
ISSN: 1972-2680
Popis: Introduction: Colletotrichum species are well-known plant pathogens, which have been increasingly reported as the cause of keratitis or subcutaneous lesions in humans. In this study we reported a rare case of fungal keratitis from Iran and reviewed the literature. Case Presentation: A 69-year-old man whose right eye was injured by herbal material was examined by slit-lamp biomicroscopy and mycology investigation of corneal scrapings was done. The grown filamentous fungal was identified as Colletotrichum gloeosporioides based on morphological characteristics and DNA sequence of the internal transcribed spacer region. The isolated strain was sensitive to amphotericin B, caspofungin, anidolafungin, micafungin, voriconazole, and relatively resistant to fluconazole, and itraconazole. Patient was successfully treated with voriconazole. Conclusions: This report highlights that the early and accurate identification and therapy can helpful to management keratitis caused by C. gloeosporioides.
Databáze: OpenAIRE