The predictive value of nasolacrimal sac biopsy in endoscopic dacryocystorhinostomy
| Autor: | Abdulkarim Hasan, Ahmed Rabie Mohammed, Ibrahim Eldsoky, Ahmed Abd Alrahman Ibrahim, Mahmoud E. Alsobky, Mohamed Hussein Abdelazim, Wael Fawzy Ismaiel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Dacryocystorhinostomy Histopathology Endoscopic DCR 03 medical and health sciences 0302 clinical medicine Epiphora Biopsy Medicine Rhinoscleroma Cohort Study Nasolacrimal sac medicine.diagnostic_test business.industry General Medicine medicine.disease Dacryocystitis Lacrimal sac Surgery medicine.anatomical_structure Nasolacrimal duct obstruction Chronic dacryocystits 030220 oncology & carcinogenesis Granuloma 030211 gastroenterology & hepatology business |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| Popis: | Background During dacryocystorhinostomy (DCR), the lacrimal sac wall biopsy is not routinely performed in our hospital, but it is recommended if there is a suspicion of underlying disease other than preoperatively or intraoperatively chronic inflammation. Objective Most of patients with epiphora have different causes of nasolacrimal duct obstruction (NLDO). This study aims to examine how important routine lacrimal sac biopsy is during endoscopic DCR surgery. Patients & methods The study included 50 patients with chronic unilateral epiphora. All patients underwent endoscopic DCR with NLD biopsy. Histopathologic analysis was performed for each specimen. Results The findings of NLD biopsy showed chronic inflammation in 33 cases (66%), chronic dacryocystitis in 9 cases (18%), dacryolith with dacryocystitis in one case, granuloma in 4 cases (8%), rhinoscleroma in 2 cases (4%), and one case had a neoplasm. Histopathologic findings were inflammatory cellular infiltrates in 56%, 30% and 14% in mild, moderate and severe chronic inflammatory state (CIS) score, respectively. Fibrosis in 18%, 20% and 62% in mild, moderate and severe CIS score, respectively. Capillary proliferation in 64%, 32% and 4% in mild, moderate and severe CIS score, respectively. Chronic inflammatory signs in 64%, 32% and 4% in mild, moderate and severe CIS score, respectively. Conclusion Although neoplasm and granuloma are rare cause of lacrimal sac or duct obstruction requiring DCR, they were detected through nasolacrimal assessment and routine intraoperative lacrimal sac biopsy. Highlights • Nasolacrimal sac biopsy in all endoscopic dacryocystorhinostomies is highly advised. • Seven patients out of 50 revealed unexpected pathology results. • Neoplasm and granuloma are detected in lacrimal sac or duct obstruction. |
| Databáze: | OpenAIRE |
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