Biosynthesis of the K99 surface antigen is repressed by alanine
| Autor: | P Klaasen-Boor, J E van Hees, F K de Graaf |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
animal diseases
Immunology Biology medicine.disease_cause Microbiology chemistry.chemical_compound Plasmid Biosynthesis Antigen medicine Escherichia coli Psychological repression Inhibitory effect Alanine chemistry.chemical_classification Antigens Bacterial Molecular biology Amino acid Kinetics Infectious Diseases chemistry Biochemistry Antigens Surface Parasitology Research Article |
| Zdroj: | Infection and immunity. 30(1) |
| ISSN: | 0019-9567 |
| Popis: | The amino acid alanine induced a direct and specific repression of the biosynthesis of the K99 surface antigen in Escherichia coli strains harboring the K99 plasmid. In minimal medium with 0.5% glucose, 1 mM L-alanine was sufficient to reduce the K99 production by about 95%. The low production of the K99 antigen by strains growing on commercially available nutrient media seemed to be a result of the inhibitory effect alanine on the K99 biosynthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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