Characteristic features of newly established specific pathogen-free albino large rabbit (JW-AKT): Comparison with Japanese White and New Zealand White rabbits
| Autor: | Yoshiko Shibata, Takahiro Obata, Megumi Yano, Keita Basaki, Naofumi Takaki, Tatsuhiro Maeda, Shinsuke Seki, Kazutoshi Nishijima, Misako Higashiya, Yukihisa Matsuda, Masao Hirao, Yasuyoshi Fukuda |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Physiology Biology Breeding Body weight JW-AKT alternative to dog Laboratory Animal Science Animals Laboratory medicine JAPANESE WHITE Animals New zealand white Protein kinase B Specific-pathogen-free Kidney General Veterinary Full Paper Body Weight Rabbit (nuclear engineering) Organ Size Specific Pathogen-Free Organisms novel rabbit model Experimental animal medicine.anatomical_structure Adipose Tissue Female Rabbits body size |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 |
| Popis: | The present study was conducted to reveal characteristic features of albino large rabbit (JW-AKT) which we formerly established a specific pathogen-free (SPF) colony. Body weights of JW-AKT rabbit at 52 weeks old was 5.7 ± 0.4 kg in males and 6.4 ± 0.4 kg in females. Weight of body, heart, lung and kidney in JW-AKT rabbit was significantly higher than in Japanese white and New Zealand white rabbits in both sexes. Though the body weight (BW) was rather lower in males, body length and brain weights tended to be higher in males than in females. Since body fat was significantly higher in females, what affects difference in BW is body fat, rather than the physical constitution of female JW-AKT rabbit. No critical sex difference was found in hematological parameters in JW-AKT rabbit. The results indicated that JW-AKT were about 1.5 times larger than the general laboratory rabbits with common properties in hematology. Thus, JW-AKT rabbit could be used as a novel SPF experimental animal model with some advantages in surgical experiments or collection of large amount of biological specimen. |
| Databáze: | OpenAIRE |
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