Observations on the pathway of exogenous C14-histamine in stimulating gastric secretion
Autor: | M. Dittbrenner, State D, Herzl Ragins, Peregrina Labay |
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Rok vydání: | 1964 |
Předmět: |
medicine.medical_specialty
Duodenum Endogeny Stimulation Biology chemistry.chemical_compound Dogs Internal medicine medicine Gastric mucosa Animals Secretion Enterochromaffin-like cell Pharmacology Carbon Isotopes Gastric Acidity Determination Gastric Juice Research digestive oral and skin physiology Rectum digestive system diseases Metabolism Endocrinology medicine.anatomical_structure chemistry Gastric Mucosa Digestion Surgery Histamine |
Zdroj: | Journal of Surgical Research. 4:164-169 |
ISSN: | 0022-4804 |
DOI: | 10.1016/s0022-4804(64)80105-0 |
Popis: | Summary o 1. After injection of C 14 -histamine, radioactivity was determined simultaneously in the gastric, duodenal and rectal mucosa, gastric juice and serum of the dog. 2. The acid secretion was measured simultaneously with the above studies. 3. When gastric secretion had ceased, the level of radioactivity in the gastric mucosa and serum was still moderately high. 4. The level of radioactivity in the gastric duodenal and rectal mucosa correlated well with the known levels of endogenous histamine in these organs. 5. After the C 14 -histamine induced secretion had ceased for one hour, stimulation with the same dose of unlabeled histamine increased the radioactivity of the juice above previous levels. |
Databáze: | OpenAIRE |
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