Combined 68Ga-DOTATOC and 18F-FDG PET Predicts a Double Component With Different Grade of a Pancreatic Neuroendocrine Tumor in a Patient With Multiple Endocrine Neoplasia Type 1
| Autor: | Céline Meyer, Anne-Cécile Paepegaey, Rossella Libé, Sébastien Gaujoux, Alexandre Rouquette |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Pancreatic neuroendocrine tumor Neuroendocrine tumors Octreotide 030218 nuclear medicine & medical imaging 18f fdg pet 68ga dotatoc 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 medicine Multiple Endocrine Neoplasia Type 1 Organometallic Compounds Humans Radiology Nuclear Medicine and imaging Multiple endocrine neoplasia Lower grade business.industry General Medicine medicine.disease Prognosis Pancreatic Neoplasms Neuroendocrine Tumors 030220 oncology & carcinogenesis Positron-Emission Tomography Radiology business |
| Zdroj: | Clinical nuclear medicine. 45(6) |
| ISSN: | 1536-0229 |
| Popis: | Managing decisions of pancreatic neuroendocrine tumors (pNETs) can be challenging because of different clinical presentations and prognosis. A 31-year-old woman with multiple endocrine neoplasia type 1, including a suspicious pNET, was assessed with Ga-DOTATOC and F-FDG PET. A high Ga-DOTATOC uptake was visualized in the entire pNET, whereas a high F-FDG PET uptake was present only in the upper part of the tumor. After surgery, pathology confirmed the pNET with a double component: an upper grade 2 with a Ki67 of 11% with the high F-FDG PET uptake, and a lower grade 1 with a Ki67 of 2%. Combined Ga-DOTATOC/F-FDG PET predicts the grade in heterogeneous pNETs. |
| Databáze: | OpenAIRE |
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