Differential response to pharmacological intervention in ADHD furthers our understanding of the mechanisms of interference control

Autor: Isabel Suarez, Aline Miquee, Aurélie Grandjean, D. Da Fonseca, Laurence Casini
Přispěvatelé: Laboratoire de Neurosciences Cognitives [Marseille] (LNC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Universidad del Norte, Barranquilla, Hôpital Salvator [CHU - APHM] (Hôpitaux Sud), ANR-15-CE28-0008,DOPCONTROL,Optimisation du contrôle cognitif : Approches comportementale, électrophysiologique et en neuroimagerie du développement normal et pathologique(2015), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Adolescent
Cognitive Neuroscience
media_common.quotation_subject
Experimental and Cognitive Psychology
Audiology
Selective inhibition
Interference (genetic)
050105 experimental psychology
03 medical and health sciences
0302 clinical medicine
Arts and Humanities (miscellaneous)
Dopamine Uptake Inhibitors
Intervention (counseling)
mental disorders
Developmental and Educational Psychology
medicine
Attention deficit hyperactivity disorder
Humans
0501 psychology and cognitive sciences
Control (linguistics)
Child
ComputingMilieux_MISCELLANEOUS
media_common
Methylphenidate
[SCCO.NEUR]Cognitive science/Neuroscience
05 social sciences
Cognition
medicine.disease
Inhibition
Psychological
Neuropsychology and Physiological Psychology
Attention Deficit Disorder with Hyperactivity
[SCCO.PSYC]Cognitive science/Psychology
Impulsive Behavior
Impulse (psychology)
Central Nervous System Stimulants
Female
Psychology
030217 neurology & neurosurgery
medicine.drug
Zdroj: Cognitive Neuropsychology
Cognitive Neuropsychology, 2021, 38 (2), pp.138-152. ⟨10.1080/02643294.2021.1908979⟩
Cognitive Neuropsychology, Taylor & Francis (Routledge), 2021, 38 (2), pp.138-152. ⟨10.1080/02643294.2021.1908979⟩
ISSN: 1464-0627
0264-3294
Popis: The deficit in "interference control" found in children with Attention Deficit Hyperactivity Disorder (ADHD) could be due to two distinct processes, which are not disentangled in most studies: a larger susceptibility to activating prepotent response impulses and a deficit in suppressing them. Here, we investigated the effect of 1/ADHD and 2/ methylphenidate (MPH), on these two components of interference control. We compared interference control between untreated children with ADHD, children with ADHD under MPH, and typically developing children performing a Simon task. The main findings were that 1/ children with ADHD were more susceptible to reacting impulsively and less efficient at suppressing impulsive actions, and 2/ MPH improved the selective inhibition of impulsive actions but did not modify the strength of response impulse. This work provides an example of how pharmacological interventions and selective responses to them can be used to investigate and further our understanding of cognitive processing.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje