Healing of experimental gingival recession defects treated with amnion allograft: Histologic and histometric analysis in dogs

Autor: Marwa Gomaa, Hoda El Guindy, Malak Shoukheba, Alaa Metwalli
Rok vydání: 2022
Předmět:
Zdroj: Journal of Oral Biosciences. 64:93-99
ISSN: 1349-0079
DOI: 10.1016/j.job.2022.01.006
Popis: This study was conducted to compare the healing response of localized gingival recession defects treated with a coronally advanced flap (CAF) and either an amnion allograft membrane (AM) or a connective tissue graft (CTG).Gingival recession defects were surgically created in six healthy mongrel dogs at the labial root surface of the maxillary canines, bilaterally. Using a split mouth design, the defects were treated with CAF and either AM (CAF/AM) or CTG (CAF/CTG). Three animals for each group were scarified at 1 and 3 months. Segments containing the defects were prepared for histological and histometric analysis.Both techniques showed similar clinical findings with adequate root coverage. Histologically, healing was characterized by the formation of new cementum and new connective tissue attachment in the CAF/AM group; in the CAF/CTG group, healing was characterized by junctional epithelium, coronally, and connective tissue fibers parallel to the root surface, apically. Histometrically, the CAF/AM group revealed a substantially shorter epithelial length and a longer, new cementum compared with those of the CAF/CTG group after a healing period of 3 months.Within the limits of this study, we concluded that the AM allograft could promote periodontal healing in gingival recession defects.
Databáze: OpenAIRE