Initial Lung Lesions in Two Calves Experimentally Infected with Haemophilus somnus
| Autor: | Henrik Jeldtoft Jensen, Conny Tegtmeier, N.E. Jensen, B. Bloch |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Lung Diseases
Original Paper Pathology medicine.medical_specialty Haemophilus Infections Lung Lymphoid Tissue animal diseases Haemophilus Cattle Diseases General Medicine Biology Haemophilus somnus Lung pathology Immunohistochemistry Microscopy Electron Lymphatic system medicine.anatomical_structure Antigen medicine Animals Cattle Female |
| Zdroj: | University of Copenhagen Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health |
| ISSN: | 0931-1793 |
| DOI: | 10.1111/j.1439-0450.1999.tb01244.x |
| Popis: | Summary The initial lung lesions in two calves intrabronchially inoculated with Haemophilus somnus are described. The animals were euthanized within 7 h after challenge. The in situ location of H. somnus and accompanying lesions were examined by light microscopy, immunohistochemistry and transmission electron microscopy (TEM). Inoculation with H. somnus resulted in the development of acute pulmonary lesions within 3.5 h. H. somnus antigen was demonstrated only within the luminal spaces of the airways and in one area of bronchio‐associated lymphoid tissue (BALT). As observed by TEM, the bacteria were phagocytized by both neutrophils and alveolar macrophages. Antigen was never demonstrated in the pulmonary intravascular macrophages. |
| Databáze: | OpenAIRE |
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