Creating Diversity from Biomass: A Tandem Bio/Metal‐Catalysis towards Chemoselective Synthesis of Densely Substituted Furans
| Autor: | Alexandre F. Trindade, Svilen P. Simeonov, Giovanni Poli, João M. J. M. Ravasco, Filipa Siopa, Carlos M. Monteiro, Julie Oble, Carlos A. M. Afonso |
|---|---|
| Přispěvatelé: | Faculdade de Farmácia da Universidade de Lisboa, Institut Parisien de Chimie Moléculaire (IPCM), Chimie Moléculaire de Paris Centre (FR 2769), Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Universidade de Lisboa (ULISBOA), Réactivité organométallique et catalyse pour la synthèse (ROCS), Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Chimie Moléculaire de Paris Centre (FR 2769), Bulgarian Academy of Sciences (BAS) |
| Rok vydání: | 2019 |
| Předmět: |
Tandem
Chemistry POLE 1 General Chemical Engineering Biomass 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Desymmetrization ROCS 0104 chemical sciences Catalysis Chemical instability Metal General Energy Biocatalysis visual_art visual_art.visual_art_medium [CHIM]Chemical Sciences Environmental Chemistry Organic chemistry General Materials Science Chemoselectivity 0210 nano-technology |
| Zdroj: | ChemSusChem ChemSusChem, ChemPubSoc Europe/Wiley, 2019, 12 (20), pp.4629--4635. ⟨10.1002/cssc.201902051⟩ |
| ISSN: | 1864-564X 1864-5631 |
| Popis: | A new chemoselective (enzymatic desymmetrization/Ru-catalyzed C-H activation) sequence to obtain differently substituted furans from the largely available 2,5-furandicarboxylic acid (FDCA) was developed. Series of di- and trisubstituted furans were prepared in very good yields and excellent chemoselectivity. This study discloses a new approach towards valorization of the furanics platform through the use of FDCA as a stable intermediate, thus circumventing the chemical instability of the parent 5-hydroxymethylfurfural. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text