Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis
| Autor: | Julia H. M. White, Giovanna Lucchini, Leland H. Johnston, Anthony L. Johnson, Paulo Plevani |
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| Rok vydání: | 1990 |
| Předmět: |
DNA Replication
Transcription Genetic DNA synthesis Genes Fungal Saccharomyces cerevisiae DNA replication Mitosis RNA Nucleotidyltransferases DNA Primase Biology Cell cycle biology.organism_classification Molecular biology Meiosis Mitotic cell cycle Gene Expression Regulation Fungal Genetics Primase DNA Fungal Molecular Biology Gene |
| Zdroj: | Molecular and General Genetics MGG. 221:44-48 |
| ISSN: | 1432-1874 0026-8925 |
| DOI: | 10.1007/bf00280366 |
| Popis: | Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis. |
| Databáze: | OpenAIRE |
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