Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions
| Autor: | Eskandar Kolvari, Ali Amoozadeh, Mahnaz Sakhdari |
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| Rok vydání: | 2021 |
| Předmět: |
Green chemistry
chemistry.chemical_classification 2 4 5-trisubstituted imidazoles Solvent free recyclable catalysts green chemistry multicomponent reactions Organic Chemistry One-pot synthesis 1 2 4 5-tetrasubstituted imidazoles Nanoparticle Sulfonic acid Catalysis QD241-441 chemistry Organic chemistry solvent-free conditions γ-fe2o3-so3h |
| Zdroj: | Heterocyclic Communications, Vol 27, Iss 1, Pp 71-78 (2021) |
| ISSN: | 2191-0197 |
| DOI: | 10.1515/hc-2020-0125 |
| Popis: | In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40–70 min for trisubstituted imidazoles and 30–40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92–98% for trisubstituted imidazoles and 94–98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free conditions, high catalytic activity, shorter reaction time, easy recovery by an external magnet, high purity, and excellent yields are some features of these reactions. |
| Databáze: | OpenAIRE |
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