Persistence of Antibody in Human Subjects for 7 to 10 Years following Administration of Combined Live Attenuated Measles, Mumps, and Rubella Virus Vaccines
| Autor: | Robert E. Weibel, Robert R. Roehm, Arlene A. McLean, Maurice R. Hilleman, Eugene B. Buynak |
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| Rok vydání: | 1980 |
| Předmět: |
Time Factors
Measles Vaccine Mumps Vaccine Antibodies Viral Vaccines Attenuated medicine.disease_cause Rubella Measles General Biochemistry Genetics and Molecular Biology Virus Immunity medicine Humans Rubella Vaccine Child Subclinical infection biology business.industry Vaccination Infant Rubella virus medicine.disease Child Preschool Immunology biology.protein Antibody business |
| Zdroj: | Experimental Biology and Medicine. 165:260-263 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-165-40967 |
| Popis: | Antibody persistence was measured in children in the open community 10.5 years after combined measles-mumps-rubella (14 children), 9 years after measles-rubella (17 children), 10.5 years after mumps-rubella (9 children), and 7 years after measles-mumps (20 children) vaccines were given. There were increases, declines, and stationary titers among the children in the serum samples taken 6 weeks after vaccination compared with those taken at later time periods. This reflected a decline in antibody in some children and subclinical natural reinfection in others. Importantly, all the children still retained detectable antibody, indicating long-term persistence of immunity by vaccination with combined virus vaccines. |
| Databáze: | OpenAIRE |
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