'Sequential multimodality stimulation' for post-stroke-hemineglect: Feasibility and outcome in a pilot randomized controlled trial
| Autor: | Sankara P. Sarma, Vaibhav Tandon, Sesh Sivadasan, Parthan T. Sakunthala, Sajith Sukumaran |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Pilot Projects Stimulation Neuropsychological Tests Outcome (game theory) law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Physiology (medical) Outcome Assessment Health Care medicine Humans Single-Blind Method Physical Therapy Modalities Aged medicine.diagnostic_test business.industry Stroke Rehabilitation Recovery of Function General Medicine Neuropsychological test Middle Aged Functional recovery Stroke Clinical trial Treatment Outcome Neurology 030220 oncology & carcinogenesis Physical therapy Post stroke Feasibility Studies Female Surgery Neurology (clinical) business Neurocognitive 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Neuroscience. 71:108-112 |
| ISSN: | 0967-5868 |
| Popis: | Objective To test the feasibility and efficacy of multimodality stimulation combined with motor tasking as a corrective strategy for hemineglect following right hemispheric ischemic strokes. Material and methods A prospective randomized controlled single blinded clinical trial was conducted over eighteen months from January 2017. All patients with right hemispheric ischemic strokes were screened for hemineglect and those fulfilling criteria were recruited and randomized. Patients under the therapy group (TG) received the intervention based on a structured protocol in addition to standard physiotherapy. The control group (CG) received standard physiotherapy alone. NIHSS, mRS and Neuropsychological test scores were recorded at different time points. The primary outcome measures (neuropsychological test scores) were compared between the two groups (Student's t-test to find out the difference in outcome measures) at one and three months post-stroke. Results Of the 14 patients recruited, data from 12 were available for analysis, 5 patients in TG and 7 in CG. There was a trend for better hemineglect and functional outcomes in TG. Conclusion Multimodality stimulation, in addition to standard physiotherapy, is feasible and potentially results in better neurocognitive and functional recovery following right hemispheric ischemic strokes. However, larger studies are warranted to prove these preliminary observations beyond doubt. |
| Databáze: | OpenAIRE |
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