Assessment of 25(OH)D vitamin concentration in plasma of residents of Lodz with metabolic syndrome in pre- and postmenopausal period
| Autor: | Sławomir Tokarski, Dariusz Moczulski, Franciszek Szatko, Małgorzata Godala, Izabela Materek-Kuśmierkiewicz, Jan Kowalski, Ewelina Gaszyńska |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Vitamin
medicine.medical_specialty Original Paper Postmenopausal women business.industry Endocrinology Diabetes and Metabolism lcsh:R Obstetrics and Gynecology menopause lcsh:Medicine vitamin D medicine.disease vitamin D deficiency metabolic syndrome Menopause chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine Vitamin D and neurology Risk factor Metabolic syndrome business International diabetes federation |
| Zdroj: | Menopause Review, Vol 13, Iss 5, Pp 293-297 (2014) Przegla̜d Menopauzalny = Menopause Review |
| ISSN: | 2299-0038 1643-8876 |
| Popis: | Introduction: Vitamin D deficiency is a risk factor for metabolic syndrome disorders and the occurrence of these disorders greatly contributes to the deficiency of vitamin D. Postmenopausal women are particularly prone to that deficiency. Aim : The aim of the study was to assess vitamin D concentration in the plasma of pre- and postmenopausal women, with or without metabolic syndrome. Material and methods : The study included 141 women aged 26-77 (the mean age 58.74 years old), divided into 4 groups depending on the pre- or postmenopausal period and diagnosed or not with metabolic syndrome according to the International Diabetes Federation criteria (2005). Vitamin D concentration was assessed by LIAISON® test using chemiluminescent immunoassay (CLIA) technology. Results: The mean vitamin D concentration was the highest among premenopausal women without metabolic syndrome (24.32 ng/ml), it was insignificantly higher than in postmenopausal women without metabolic syndrome (23.52 ng/ml) and significantly higher than in both groups with metabolic syndrome – premenopausal (19.86 ng/ml) and postmenopausal women (9.32 ng/ml). The recommended plasma 25(OH)D concentration was not found in any of postmenopausal women with diagnosed metabolic syndrome. Conclusions : Postmenopausal women with metabolic syndrome had a significantly lower 25(OH)D vitamin concentration in plasma than postmenopausal women without metabolic syndrome. The frequency of vitamin D deficiency in women with metabolic syndrome was very high, significantly higher than in women without metabolic syndrome. |
| Databáze: | OpenAIRE |
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