Different Attenuation Models of Diffusion-Weighted MR Imaging for the Differentiation of Benign and Malignant Musculoskeletal Tumors
| Autor: | Sevtap Arslan, Kemal Kosemehmetoglu, Mehmet Ayvaz, Adalet Elcin Yildiz, Fatma Bilge Ergen, Jale Karakaya, Ustun Aydingoz, G. Aydın |
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| Rok vydání: | 2021 |
| Předmět: |
education.field_of_study
business.industry Intraclass correlation Population Reproducibility of Results Subgroup analysis Motion Diffusion Magnetic Resonance Imaging Neoplasms Mann–Whitney U test Effective diffusion coefficient Medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Stage (cooking) business education Nuclear medicine Intravoxel incoherent motion Diffusion MRI |
| Zdroj: | Journal of magnetic resonance imaging : JMRIREFERENCES. 55(2) |
| ISSN: | 1522-2586 |
| Popis: | BACKGROUND Several functional imaging techniques, including monoexponential diffusion-weighted imaging (m-DWI), intravoxel incoherent motion (IVIM), and diffusion kurtosis (DK) imaging, have been used in differentiating benign and malignant musculoskeletal tumors. Combining all three techniques in the same study population may improve differentiation. PURPOSE To compare the diagnostic performance of m-DWI, IVIM, and DK models and their combinations in differentiating benign and malignant musculoskeletal tumors. STUDY TYPE Prospective. POPULATION Fifty patients with benign and malignant musculoskeletal tumors divided into nonmyxoid and nonchondroid and myxoid and/or chondroid subgroups. FIELD STRENGTH/SEQUENCE A 1.5 T/m-DWI, IVIM, and DK single-shot spin-echo echo-planar sequences. ASSESSMENT Minimum and volumetric values of apparent diffusion coefficient (ADC), pure molecular diffusion (Divim ), pseudodiffusion (D*), perfusion fraction (f), diffusion coefficient for kurtosis model (DK ), and Kurtosis (K) were compared between all benign and malignant tumors. Subgroup analysis was also performed for nonmyxoid and nonchondroid and myxoid and/or chondroid tumors. STATISTICAL TESTS Independent samples t-test, Mann-Whitney U test, intraclass correlation coefficient, ROC analysis, and logistic regression analysis. A P value |
| Databáze: | OpenAIRE |
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