Tc-99m DTPA renal scintigraphy using deconvolution analysis with six functional images of the mean time to evaluate acute pyelonephritis
| Autor: | Basić M, Nizić Lj, Dražen Huić, Danko Milosevic, M. Poropat, Damir Dodig, Ana Votava-Raić, Medvedec M, K Vrljicak, Danica Batinić, Tezak S |
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| Rok vydání: | 1999 |
| Předmět: |
Male
Pathology medicine.medical_specialty Kidney Cortex Renal cortex Urinary system chemistry.chemical_element Scintigraphy Technetium Kidney Image Interpretation Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Gamma Cameras Child Urinary Tract Technetium Tc 99m Pentetate Escherichia coli Infections medicine.diagnostic_test Pyelonephritis business.industry Radioisotope renography Infant General Medicine medicine.disease medicine.anatomical_structure chemistry Child Preschool Technetium Tc 99m Dimercaptosuccinic Acid Female Radiopharmaceuticals Nuclear medicine business Radioisotope Renography Kidney disease |
| Zdroj: | Clinical nuclear medicine. 24(2) |
| ISSN: | 0363-9762 |
| Popis: | In 38 children with proved P-fimbriated Escherichia coli acute pyelonephritis, Tc-99m DTPA dynamic renal scintigraphy in the zoom mode using deconvolution analysis was performed, and the results were compared with those of Tc-99m DMSA scans. From the dynamic study, six functional images of the mean time were generated. Each functional image was analyzed separately to search for focal areas of increased mean time within the kidney contour, especially over the kidney parenchyma. Time-activity curves from these areas were generated and analyzed. Tc-99m DMSA scintigraphy showed generalized or focal decreased uptake in 32 (41.8%) kidneys, and deconvolution analysis of Tc-99m DTPA scintigraphy revealed pathologic renographic curves in 58 (77.6%) kidneys. Prolonged whole-kidney and normal renal parenchymal transit times (dilatation without obstruction) were found in 38 (50%) kidneys, whereas prolonged whole-kidney and renal parenchymal transit times (dilatation with obstruction) were observed in 20 (27.6%) kidneys. Separate analysis of each of the six functional images of the mean time showed focal areas of increased mean time in the kidney parenchyma of 11 kidneys. In five cases, time-activity curves from these areas showed a sharp increase of activity on the descending part of the curve, which might reflect the return of urine from the collecting system into kidney cortex (i.e., intrarenal reflux). These results showed that in a urinary tract with acute pyelonephritis, urodynamic changes may lead to obstructive nephropathy and intrarenal reflux. Tc-99m DTPA renal scintigraphy in the zoom mode using deconvolution analysis with six functional images of the mean time has proved to be a valuable method to evaluate acute pyelonephritis, thus allowing dynamic and morphologic analysis of the urinary tract at the same time. |
| Databáze: | OpenAIRE |
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