Blood cells as biological trait markers in affective disorders

Autor: Giovanni Muscettola, Clemente Patrizio Giannini, Andrea Di Lauro
Rok vydání: 1984
Předmět:
Zdroj: Journal of Psychiatric Research. 18:447-456
ISSN: 0022-3956
DOI: 10.1016/0022-3956(84)90032-3
Popis: Data are reviewed on platelet monoamine oxidase activity, red blood cell/plasma lithium ratio, and tritiated imipramine binding to platelet membranes as trait markers for affective disorders. The results of various studies are not in agreement. Differences in methodological procedure are probably central to such discrepancies. At the present time, no single biological abnormality of blood cells has proved to be a trait marker for affective disorders; thus their use to identify vulnerability to mood disorders or predict favourable response to pharmacological treatment appears to be premature.
Databáze: OpenAIRE