Infantile osteopetrosis; bone marrow transplantation from a cousin donor
| Autor: | W. D. Fergusson, G. Morrell, Andrew M. Will, D. I. K. Evans, G. M. Taylor, S. P. Dearden, M. Super, S. Simon, R. F. Stevens, I. H. Brown |
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| Rok vydání: | 1995 |
| Předmět: |
HLA-DP Antigens
medicine.medical_specialty Cousin Consanguinity Human leukocyte antigen HLA Antigens medicine Humans HLA-DP beta-Chains Bone Marrow Transplantation business.industry Infant Osteopetrosis medicine.disease Osteochondrodysplasia Pedigree Histocompatibility Surgery Transplantation surgical procedures operative medicine.anatomical_structure HLA-B Antigens Pediatrics Perinatology and Child Health Female Bone marrow business Research Article |
| Zdroj: | Archives of Disease in Childhood. 73:453-455 |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/adc.73.5.453 |
| Popis: | The successful correction of infantile osteopetrosis in an Asian child by bone marrow transplantation (BMT) from an HLA-A,B matched cousin donor is reported. Retrospective HLA molecular analysis revealed that patient and donor were incompatible for HLA-DPB1. Donor type cells detected in the patient after transplantation indicate successful engraftment. The patient is currently alive and well. |
| Databáze: | OpenAIRE |
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