Oxidative Stress Profile of Mothers and Their Offspring after Maternal Consumption of High-Fat Diet in Rodents: A Systematic Review and Meta-Analysis
| Autor: | Rafaianne Queiroz Moraes-Souza, Thaigra de Sousa Soares, Gustavo Tadeu Volpato, Giovana Vesentini, Verônyca Gonçalves Paula, Débora Cristina Damasceno, Rafael Bottaro Gelaleti, Yuri Karen Sinzato |
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| Přispěvatelé: | Universidade Estadual Paulista (UNESP), Universidade Federal de Mato Grosso do Sul (UFMS), Institut Universitaire de Gériatrie de Montréal |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Aging
Article Subject Offspring Physiology Rodentia Diet High-Fat medicine.disease_cause Biochemistry Superoxide dismutase Mice chemistry.chemical_compound Pregnancy Lactation medicine Animals QH573-671 biology business.industry Cell Biology General Medicine medicine.disease Malondialdehyde Rats Oxidative Stress medicine.anatomical_structure chemistry Meta-analysis biology.protein Gestation Female Cytology business Oxidative stress Research Article |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Oxidative Medicine and Cellular Longevity, Vol 2021 (2021) Oxidative Medicine and Cellular Longevity |
| ISSN: | 1942-0900 |
| DOI: | 10.1155/2021/9073859 |
| Popis: | Made available in DSpace on 2022-04-29T08:37:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Maternal exposure to the high-fat diet (HFD) during gestation or lactation can be harmful to both a mother and offspring. The aim of this systematic review was to identify and evaluate the studies with animal models (rodents) that were exposed to the high-fat diet during pregnancy and/or lactation period to investigate oxidative stress and lipid and liver enzyme profile of mothers and their offspring. The electronic search was performed in the PUBMED (Public/Publisher MEDLINE), EMBASE (Ovid), and Web of Science databases. Data from 77 studies were included for qualitative analysis, and of these, 13 studies were included for meta-analysis by using a random effects model. The pooled analysis revealed higher malondialdehyde levels in offspring of high-fat diet groups. Furthermore, the pooled analysis showed increased reactive oxygen species and lower superoxide dismutase and catalase in offspring of mothers exposed to high-fat diet during pregnancy and/or lactation. Despite significant heterogeneity, the systematic review shows oxidative stress in offspring induced by maternal HFD. Laboratory of Experimental Research on Gynecology and Obstetrics Gynecology Postgraduate Course on Tocogynecology Botucatu Medical School São Paulo State University (Unesp), São Paulo State Laboratory of System Physiology and Reproductive Toxicology Institute of Biological and Health Sciences Federal University of Mato Grosso (UFMT), Mato Grosso State School of Rehabilitation Faculty of Medicine Université de Montréal Research Center Institut Universitaire de Gériatrie de Montréal Laboratory of Experimental Research on Gynecology and Obstetrics Gynecology Postgraduate Course on Tocogynecology Botucatu Medical School São Paulo State University (Unesp), São Paulo State |
| Databáze: | OpenAIRE |
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