SERUM FATTY ACID PATTERN IN CHRONIC ALCOHOLICS AFTER ACUTE ABUSE
| Autor: | Sven J. Dencker, Jir̂í Tichý, Christer Alling, Lars Svennerholm |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Chromatography Gas Chromatography Paper Linoleic acid Blood lipids Alcohol Arachidonic Acids chemistry.chemical_compound Internal medicine Internal Medicine Humans Medicine Phospholipids Serum cholesterol chemistry.chemical_classification business.industry Chronic alcoholic Fatty acid Middle Aged Lipids Fats Unsaturated Alcoholism Cholesterol Endocrinology Linoleic Acids Biochemistry chemistry Chromatography Thin Layer Fatty acid composition business Alcoholic Intoxication Gas liquid chromatographic |
| Zdroj: | Acta Medica Scandinavica. 185:99-105 |
| ISSN: | 0001-6101 |
| DOI: | 10.1111/j.0954-6820.1969.tb07303.x |
| Popis: | Serum lipids were studied in 14 chronic alcoholic males, aged 30–56 years, after a bout of drinking. Ten male ward assistants, aged 22–58 years, served as controls. 1. No definite differences were found between alcoholics and controls in the level of total lipids and phospholipids in serum. There was a significant increase of serum cholesterol in the alcoholics compared to the controls. 2. Gas liquid, paper and thin-layer chromatographic determinations of the fatty acid composition of serum cholesteryl esters demonstrated significantly lower figures for linoleic acid and significantly higher figures for monounsaturated fatty acids in the alcoholics. 3. Gas liquid chromatographic determinations of the fatty acid composition of phosphoglycerides demonstrated that the decrease of linoleic acid and the increase of monounsaturated fatty acids were even more pronounced than in the cholesteryl esters. 4. Five alcoholics who were restudied two weeks after admission showed a normalization of the fatty acid pattern. The influence of diet and alcohol on the lipid pattern is discussed. |
| Databáze: | OpenAIRE |
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