Hypercohones A–C, acylphloroglucinol derivatives with homo-adamantane cores from Hypericum cohaerens
| Autor: | Xing-Wei Yang, Huan Wang, Qin-Shi Zhao, Xia Liu, Chao-Qun Chen, Jing-Jing Zhang, Gang Xu, Li-Xin Yang, Jun-Zeng Ma, Chun-Yan Wu |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pharmacology
biology Traditional medicine Stereochemistry Adamantane Organic Chemistry Pharmacology toxicology adamantane Regular Article Plant Science Toxicology biology.organism_classification Hypericum cohaerens Biochemistry Analytical Chemistry chemistry.chemical_compound acylphloroglucinol hypercohone chemistry Plant biochemistry Hypericum Human cancer Food Science |
| Zdroj: | Natural Products and Bioprospecting |
| ISSN: | 2192-2209 2192-2195 |
| DOI: | 10.1007/s13659-013-0032-9 |
| Popis: | Three new homo-adamantanyl type natural products were derived from polyprenylated polycyclic acylphloroglucinol. Hypercohones A-C (1–3), along with five other known hypercohones (4–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of 1–3 were elucidated on the basis of comprehensive spectroscopic analysis. The inhibitory activities of these isolates against five human cancer cell lines in vitro were tested. Electronic Supplementary Material Supplementary material is available for this article at 10.1007/s13659-013-0032-9 and is accessible for authorized users. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink