Peroral endoscopic myotomy as treatment for Zenker's diverticulum (Z-POEM): a multi-center international study
Autor: | Jorge Vargas-Madrigal, Carlos Valenzuela-Salazar, Mahmoud Wahba, Bahri Abayli, Reem Ezzat Mahdy, Ahmed Alzamzamy, J.J. Herrera-Esquivel, Kareem Essam, Ahmad Madkour, Zaher Houmani, Tarik Akar, Mouen A. Khashab, Andres Rodriguez-Parra, Ignacio Del Rio-Suarez, Shaimaa Elkholy, Süleyman Günay, Roberto Delano-Alonso, Mohamed El-Sherbiny, Mohammad A Elkady |
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Rok vydání: | 2020 |
Předmět: |
Myotomy
Male medicine.medical_specialty Zenker Diverticulum medicine.medical_treatment 03 medical and health sciences Zenker's diverticulum 0302 clinical medicine medicine Humans Adverse effect Digestive System Surgical Procedures Procedure time medicine.diagnostic_test business.industry Gastroenterology Endoscopy medicine.disease Dysphagia Surgery Treatment Outcome Cardiothoracic surgery 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female medicine.symptom business Diverticulum |
Zdroj: | Esophagus : official journal of the Japan Esophageal Society. 18(3) |
ISSN: | 1612-9067 |
Popis: | Peroral endoscopic myotomy for the treatment of Zenker’s diverticulum (Z-POEM) is a novel technique that has been described in several recent reports. This method utilizes the third space (submucosal layer) to create a tunnel to facilitate complete visualization of the septum and hence cutting it entirely. Conventional endoscopic septotomy carries the risk of recurrence due to incomplete visualization of the septum. While surgical correction is a risky and lengthy procedure in old comorbid patients with Zenker’s diverticulum. The aim of this study is to assess the efficacy and safety of Z-POEM. The study enrolled 24 patients diagnosed with Zenker’s diverticulum (ZD) who underwent Z-POEM at seven independent endoscopy centers in five different countries. Mean patient age ± standard deviation (SD) was 74.3 ± 11 years. Most of the patients were males (n = 20, 83.3%); four (16.7%) were females. More than 50% of the patients (n = 14, 58.3%) had associated comorbidities. The mean size of the diverticula was 4 cm (range 2–7 cm). The Kothari-Haber Score was used to assess clinical symptoms; values ranged from 6 to 14 (median = 9). We achieved 100% technical success with a median procedure time of 61 min and no adverse events. Median hospital stay was 1 day (range 1–5 days). There is a significant reduction in the Kothari-Haber Score after Z-POEM (P |
Databáze: | OpenAIRE |
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