Functions of peripheral-blood monocytes and granulocytes in cutaneous T-cell lymphoma
| Autor: | W.A. Vloten, Peter C. J. Leijh, R. Furth, L. Hamminga, A. Blussé Oud Alblas |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Male Staphylococcus aureus Skin Neoplasms Lymphoma Monocyte chemotaxis T-Lymphocytes Phagocytosis Chemokinesis Dermatology Biology Granulocyte Monocytes Leukocytes medicine Humans Aged Monocyte Cutaneous T-cell lymphoma Chemotaxis Middle Aged medicine.disease Chemotaxis Leukocyte medicine.anatomical_structure Immunology Female Intracellular Granulocytes |
| Zdroj: | British Journal of Dermatology. 107:157-164 |
| ISSN: | 1365-2133 0007-0963 |
| Popis: | SUMMARY Granulocyte and monocyte functions (phagocytosis, intracellular killing, chemokinesis and chemotaxis) and the opsonic and chemotactic activity of the serum of twenty-two patients with cutaneous T-cell lymphoma were assessed. Granulocyte functions were within the normal control range in most cases. The monocyte functions showed more variation in the test results; in six out of twenty-two patients intracellular killing of Staphylococcus aureus was depressed and in four out of ten patients a disturbance in monocyte chemotaxis was found. Two patients with a decreased chemotactic response also had an impaired capacity to kill S. aureus. No correlation was found between the cell disturbance and susceptibility to infection, stage of the disease, or clinical course in these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text