Study of serum metabolic profiles of patients with non-small cell lung cancer with special emphasis on the smoking status of patients
| Autor: | Jan Matysiak, Zenon J. Kokot, Wojciech Dyszkiewicz, Agnieszka Klupczynska, Halina Batura-Gabryel, Mariusz Kasprzyk, Marcin Grabicki |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Cancer Omics medicine.disease metabolomics 03 medical and health sciences lung cancer 0302 clinical medicine Metabolomics 030228 respiratory system 030220 oncology & carcinogenesis Internal medicine Cancer cell chronic-obstructive pulmonary disease Medicine Smoking status Non small cell business Lung cancer Metabolic profile mass spectrometry |
| Zdroj: | Journal of Medical Science, Vol 88, Iss 1 (2019) |
| ISSN: | 2353-9801 2353-9798 |
| Popis: | The project entitled “Study of serum metabolic profiles of patients with non-small cell lung cancer with special emphasis on the smoking status of patients” is a study based on metabolomics, which is the latest of the “omics” technologies and involves a comprehensive analysis of small molecule metabolites of a specific biological sample. High-throughput and sensitive analytical techniques used in metabolomic investigations are powerful tools in the field of oncology and aids understanding what is happening in cancer cells and searching for new cancer markers. The aim of the project is to determine whether lung cancer patients have a distinct serum metabolic profile and whether this profile is associated with patients’ smoking status. The application of liquid chromatography-high-resolution mass spectrometry-based methodology along with advanced statistical methods will enable to select potential molecules that can be useful in early lung cancer detection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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