Sequence comparison of the dopamine receptor D4 exon III repetitive region in several species of the order Carnivora
| Autor: | Naoto Matsuura, Toshio Tsubota, Yuichi Murayama, Toshiroh Iwasaki, Hitoshi Kitagawa, Shin'ichi Ito, Miho Inoue-Murayama |
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| Rok vydání: | 2002 |
| Předmět: |
Repetitive Sequences
Amino Acid ved/biology.organism_classification_rank.species Carnivora Molecular Sequence Data Biology Polymerase Chain Reaction Receptors Dopamine Exon Dogs Species Specificity mental disorders parasitic diseases Dopamine receptor D4 Animals Amino Acid Sequence Allele Gene Peptide sequence Sequence (medicine) Genetics Polymorphism Genetic Wolves General Veterinary Sequence Homology Amino Acid ved/biology Exons Gray wolf biology.protein Cats Raccoons Sequence Alignment Ursidae |
| Zdroj: | The Journal of veterinary medical science. 64(8) |
| ISSN: | 0916-7250 |
| Popis: | It was previously demonstrated that the dog dopamine receptor D4 (DRD4) gene is polymorphic in terms of the repeat number and/or order of 39- and 12-bp sequences located in the third exon. To examine whether or not the repetitive region is present in other species of the order Carnivora, the homologous region of DRD4 genes were sequenced in the gray wolf, raccoon dog, Asiatic black bear, common raccoon and domestic cat. In the family Canidae, the wolf had an identical sequence to that of the dog 447b allele, and a repetitive sequence similar to the dog DRD4 was also recognized in the raccoon dog. On the other hand, no obvious repeated structure was observed in the sequences of the bear, raccoon and cat. |
| Databáze: | OpenAIRE |
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