Dual-Layer Spectral CT Imaging of Upper Aerodigestive Tract Cancer: Analysis of Spectral Imaging Parameters and Impact on Tumor Staging
| Autor: | N.M. Parry, Trevor William Watkins, C. Jeavon, I. Fomin, L. Du, Charlie Chia-Tsong Hsu, C. Buchan, R.I. Aviv, Y. Nae |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
chemistry.chemical_element Tumor Staging Iodine medicine Humans Radiology Nuclear Medicine and imaging Head & Neck Neoplasm Staging Retrospective Studies Receiver operating characteristic Squamous Cell Carcinoma of Head and Neck business.industry Area under the curve Cancer Dual layer medicine.disease Head and neck squamous-cell carcinoma Spectral imaging chemistry Head and Neck Neoplasms Neurology (clinical) Tomography X-Ray Computed business Nuclear medicine |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X 0195-6108 |
| Popis: | BACKGROUND AND PURPOSE: Dual-layer spectral CT is a novel technology that utilized conventional single-tube CT acquisition with a dual-layer detector for the separation of high and low-energy photons to create spectral data for material decomposition. We evaluated the spectral parameters of iodine density and Z-effective values in primary head and neck squamous cell carcinoma and determined its impact on local tumor staging. MATERIALS AND METHODS: Twenty-one patients with primary head and neck squamous cell carcinoma and 15 healthy controls were retrospectively evaluated. Iodine density (milligram/milliliter) and Z-effective values were compared quantitatively between head and neck squamous cell carcinoma and normal neck mucosa. The receiver operating characteristic area under the curve determined the diagnostic performance of the spectral data for local staging. We compared conventional CT images without and with iodine density and Z-effective images to determine its impact on local tumor staging. RESULTS: Primary head and neck squamous cell carcinoma showed higher mean iodine density (2.01 [SD, 0.26] mg/mL, P |
| Databáze: | OpenAIRE |
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