Modulation of growth factor action by the extracellular matrix

Autor:	George Panayotou, Wolf Oehrl
Rok vydání:	2008
Předmět:	biology Growth factor medicine.medical_treatment Cell Biology Fibroblast growth factor Biochemistry Cell biology Extracellular Matrix Extracellular matrix Rheumatology Cell surface receptor biology.protein Extracellular medicine Animals Humans Intercellular Signaling Peptides and Proteins Orthopedics and Sports Medicine Receptors Growth Factor Signal transduction Autocrine signalling Molecular Biology Protein Kinases Platelet-derived growth factor receptor Signal Transduction
Zdroj:	Connective tissue research. 49(3)
ISSN:	1607-8438
Popis:	Growth factors were historically defined as molecules produced by the body to regulate cell growth and proliferation. After the identification of their receptors and the intracellular signaling machinery they activate, it is now clear that they are involved in the regulation of multiple processes essential for development and normal tissue function. The present review gives a brief overview of growth factor action. Receptor activation and signaling are discussed, highlighting the role of extracellular matrix interactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e714eca90c3fde1398dab80b8ef6da3 https://pubmed.ncbi.nlm.nih.gov/18661330 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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