Unilateral axillary adenopathy induced by COVID-19 vaccine: US follow-up evaluation
| Autor: | Arlette Elizalde, Ignacio Soriano, Paola Leonor Quan, Alba Cristina Igual-Rouilleault, Luis Pina, Alejandro Fernández-Montero |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
COVID-19 Vaccines Axillary lymph nodes Wilcoxon signed-rank test Lymphadenopathy Ultrasound medicine Axillary Lymphadenopathy Unilateral axillary lymphadenopathy Humans Radiology Nuclear Medicine and imaging Breast Lymph node Volunteer BNT162 Vaccine business.industry SARS-CoV-2 Incidence (epidemiology) COVID-19 General Medicine Vaccination medicine.anatomical_structure mRNA vaccine Mann–Whitney U test Radiology business Follow-Up Studies |
| Zdroj: | European Radiology Dadun. Depósito Académico Digital de la Universidad de Navarra instname |
| ISSN: | 1432-1084 0938-7994 |
| Popis: | Objectives This study was conducted in order to investigate COVID-19 vaccine influence on unilateral axillary lymph nodes, comparing nodal basal features with their characteristics after the first and second vaccination dose. Methods Ninety-one volunteer employees from our center who participated in the BNT162b2 (Pfizer-BioNTech) vaccination campaign were prospectively recruited. A total of three axillary ultrasound evaluations of the ipsilateral vaccinated arm were performed: before vaccination, the week after the first dose and the week after the second dose. The following findings were recorded: the total number of visible nodes, the maximum measurements of the diameter and cortex, Bedi’s classification, and color Doppler evaluation. The collected data were compared using paired-sample Student’s t-test for quantitative continuous variables and Wilcoxon rank-sum test for ordinal variables. Additional analyses were performed after classifying patients according to the previous history of COVID-19 disease. Differences among both groups were evaluated with the Mann–Whitney U test. Variables with a p value Results Comparative analyses between the three US examinations showed a statistically significant augmentation of total visible nodes, maximum diameter, cortical thickness, grade of Bedi’s classification, and Doppler signal (p Conclusions According to our results, both doses of COVID-19 vaccine induced an increase of all axillary lymph node parameters with statistically significant differences, especially in coronavirus-naïve patients. Key Points • Pfizer COVID-19 vaccine induces a high incidence of ipsilateral axillary lymphadenopathy. • US scan identified an increase of all lymph nodes parameters, especially in coronavirus-naïve patients. |
| Databáze: | OpenAIRE |
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