Atopic dermatitis is associated with reduced corneodesmosin expression: role of cytokine modulation and effects on viral penetration
Autor: | Un Ha Lee, Donald Y.M. Leung, D.J. Kim, Young Min Ye, Y.G. Cho, Byung Eui Kim |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Epidermal barrier integumentary system medicine.medical_treatment Eczema Inflammation Dermatology Atopic dermatitis Biology medicine.disease_cause medicine.disease Dermatitis Atopic Corneodesmosin 03 medical and health sciences Viral penetration 030104 developmental biology Cytokine Allergen Immunology medicine Cytokines Humans medicine.symptom |
Zdroj: | The British journal of dermatology. 176(2) |
ISSN: | 1365-2133 |
Popis: | The skin epidermal barrier plays a critical role in preventing allergen and microbial penetration into the human body.1 Atopic dermatitis (AD) is characterized by epidermal barrier defects and recurrent microbial skin infections.1 Recent studies indicate that defects in epidermal barrier function contribute greatly to the initiation and perpetuation of skin inflammation in AD.2 This article is protected by copyright. All rights reserved. |
Databáze: | OpenAIRE |
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