Interaction between Sodium Hypochlorite and Chlorhexidine Gluconate
| Autor: | Sheela Manek, Edward D. Fillery, Bettina Basrani, Aldo Manzur, Rana N.S. Sodhi |
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| Rok vydání: | 2007 |
| Předmět: |
Aniline Compounds
Dose-Response Relationship Drug Root Canal Irrigants Serial dilution Sodium Hypochlorite Chlorhexidine Inorganic chemistry Dye Dilution Technique Color Spectrometry X-Ray Emission chemistry.chemical_compound chemistry Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Sodium hypochlorite Chlorhexidine gluconate Root canal irrigant medicine Chemical Precipitation Drug Interactions General Dentistry medicine.drug Nuclear chemistry |
| Zdroj: | Journal of Endodontics. 33:966-969 |
| ISSN: | 0099-2399 |
| DOI: | 10.1016/j.joen.2007.04.001 |
| Popis: | The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) results in the formation of a precipitate. The aim of this study was to determine the minimum concentration of NaOCl required to form a precipitate with 2.0% CHX. This was accomplished with a serial dilution technique. X-ray photon spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) were used to qualify and quantify the precipitate. A color change and precipitate were induced in 2.0% CHX by 0.023% and 0.19% NaOCl, respectively. Both XPS and TOF-SIMS showed the presence of para-chloroaniline in an amount directly related to the concentration of NaOCl used. Until this precipitate is studied further, its formation should be avoided by removing the NaOCl before placing CHX into the canal. |
| Databáze: | OpenAIRE |
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