Target-site resistance to neonicotinoids

Autor:	Russell Slater, Stefano Rendine, Andrew J. Crossthwaite, Marco Stenta
Rok vydání:	2014
Předmět:	Genetics Resistance (ecology) Short Communication Biophysics Neonicotinoid Cell Biology Biology Bioinformatics Biochemistry Nicotinic acetylcholine receptor Nicotinic agonist Target site Excitatory postsynaptic potential PEST analysis Application methods
Zdroj:	Journal of Chemical Biology. 7:125-128
ISSN:	1864-6166 1864-6158
Popis:	Neonicotinoid insecticides selectively target the invertebrate nicotinic acetylcholine receptor and disrupt excitatory cholinergic neurotransmission. First launched over 20 years ago, their broad pest spectrum, variety of application methods and relatively low risk to nontarget organisms have resulted in this class dominating the insecticide market with global annual sales in excess of $3.5 bn. This remarkable commercial success brings with it conditions in the field that favour selection of resistant phenotypes. A number of important pest species have been identified with mutations at the nicotinic acetylcholine receptor associated with insensitivity to neonicotinoids. The detailed characterization of these mutations has facilitated a greater understanding of the invertebrate nicotinic acetylcholine receptor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e627fe5599821e53fd5bd9e44d6e56d https://doi.org/10.1007/s12154-014-0116-y Zobrazit plný text záznamu Full text from SpringerLink