Unexpected diagnosis for a gastric polyp: Granular cell tumor: Case report and review of the literature
| Autor: | Oana Popa, Alis Dema, Robert Alexandru Barna, Andrei Dorel Plopeanu, Iulia Maria Ratiu, Sorina Tăban |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Cancer Research Pathology medicine.medical_specialty S100 protein inhibin alpha 03 medical and health sciences granular cell tumor 0302 clinical medicine Immunology and Microbiology (miscellaneous) Medicine Esophagus Gastrointestinal tract Granular cell tumor business.industry Stomach Cancer Soft tissue General Medicine Articles medicine.disease 030104 developmental biology medicine.anatomical_structure Gastric Polyp endoscopic submucosal dissection 030220 oncology & carcinogenesis business gastric cardia S100 |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| Popis: | A granular cell tumor (GCT) is a rare neoplasia that originates from Schwann cells. It usually appears in the skin or soft tissues, but it may occur anywhere in the body. The gastrointestinal tract is an unusual developmental site for a GCT, the esophagus being the most common site of origin for this tumor. The stomach is one of the most unique sites of origin for GCT, with less than 80 cases being mentioned in the literature. Histologically, GCTs consist of fusiform and polygonal cells, with granular cytoplasm, arranged in compact 'nests'. Immunohistochemically, these tumors show positivity for S100 protein, CD68, CD56 and, in a smaller percentage, they are positive for other antibodies, most notably inhibin alpha. We report the case of a 52-year-old woman with a solitary GCT that had developed in the gastric cardia, discovered on a routine gastroscopy and successfully treated by endoscopic submucosal dissection. |
| Databáze: | OpenAIRE |
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