The Relationship Between Pre-existing Diabetes Mellitus and the Severity of Acute Pancreatitis: Report From a Large International Registry
| Autor: | Sorin T. Barbu, Peter Lee, Miguel Ferreira Bogado, Mahesh Kumar Goenka, Pedram Paragomi, Shyam Thakkar, Konstantinos Triantafyllou, Phil A. Hart, Carlos Ocampo, Georgios I. Papachristou, Dhiraj Yadav, Kwonho Jeong, Haq Nawaz, Rakesh Kochhar, Vikesh K. Singh, Rupjyoti Talukdar, Livia Archibugi, Ioannis Pothoulakis, Bechien U. Wu, Gregory A. Cote, Aiste Gulla, Tyler Stevens, Darwin L. Conwell, Mario Pelaez-Luna, Frederico G.S. Toledo, Alice Hinton, Enrique de-Madaria, Jose A Gonzalez, Narcis O. Zarnescu, Silvia C. Gutierrez, Jeffrey J. Easler |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Etiology Endocrinology Diabetes and Metabolism Severity of Illness Index Article law.invention law Diabetes mellitus Internal medicine medicine Prevalence Humans Registries Risk factor Mortality Aged Retrospective Studies Hepatology business.industry Confounding Diabetes Gastroenterology Middle Aged medicine.disease Intensive care unit Systemic Inflammatory Response Syndrome Systemic inflammatory response syndrome Hospitalization Diabetes Mellitus Type 2 Pancreatitis Acute Disease Acute pancreatitis Female business |
| Zdroj: | Pancreatology PANCREATOLOGY r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante instname |
| ISSN: | 1424-3903 |
| Popis: | BACKGROUND/OBJECTIVES: The relationship between pre-existing diabetes mellitus (DM) and acute pancreatitis (AP) severity has not been established. We assessed the impact of pre-existing DM on AP severity in an international, prospectively ascertained registry. METHODS: APPRENTICE registry prospectively enrolled 1543 AP patients from 22 centers across 4 continents (8 US, 6 Europe, 5 Latin America, 3 India) between 2015 and 2018, and collected detailed clinical information. Pre-existing DM was defined a diagnosis of DM prior to AP admission. The primary outcome was AP severity defined by the Revised Atlanta Classification (RAC). Secondary outcomes were development of systemic inflammatory response syndrome (SIRS) or intensive care unit (ICU) admission. RESULTS: Pre-existing DM was present in 270 (17.5%) AP patients, of whom 252 (93.3%) had type 2 DM. Patients with pre-existing DM were significantly (p |
| Databáze: | OpenAIRE |
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