Identification of a ‘Disease-Associated’ Antigen in Pigeon Breeder’s Disease by Western Blotting
| Autor: | P. M. de Beer, J R Joubert, Patrick J. Bouic |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Male
Allergy Molecular mass Blotting Western Immunology food and beverages General Medicine Disease Biology medicine.disease Asymptomatic Molecular Weight Blot Bird fancier's lung Bird Fancier's Lung Antigen Immunopathology medicine Animals Humans Immunology and Allergy Electrophoresis Polyacrylamide Gel Antigens medicine.symptom |
| Zdroj: | International Archives of Allergy and Immunology. 91:343-347 |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000235139 |
| Popis: | Sera from 9 symptomatic and 7 asymptomatic pigeon breeders were analyzed for their reactivity to pigeon serum by western blotting. All 9 symptomatic sera (9/9; 100%) and only 4 of 7 (57%) asymptomatic sera revealed specific antibodies. The immunoreactivity patterns of the sera varied: the majority of the sera reacted to antigens having molecular weights of 220 kD or more (9/16 sera), 98 kD (8/16 sera), and 86 kKD (8/16 sera). However, only sera from symptomatic breeders recognized an antigen of approximate molecular weight of 29–32 kD (9/9; 100% of symptomatics). We conclude that this antigen is ‘disease associated’ and may be useful in the diagnosis of pigeon breeder’s disease. |
| Databáze: | OpenAIRE |
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