The pacemaker cell of the sinoatrial node of the rabbit
| Autor: | E. M. Burns, L. S. D'Agrosa, J. J. Taylor |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
inorganic chemicals
endocrine system medicine.medical_specialty animal structures Physiology Cell Action Potentials In Vitro Techniques Biology Pacemaker potential Lanthanum Physiology (medical) Internal medicine medicine Animals Pacemaker cell Sinoatrial Node Sinoatrial node Rabbit (nuclear engineering) Iontophoresis Cell biology Microscopy Electron Pacemaker action potential Endocrinology medicine.anatomical_structure Cytoplasm Rabbits Cardiology and Cardiovascular Medicine |
| Zdroj: | American Journal of Physiology-Heart and Circulatory Physiology. 235:H407-H412 |
| ISSN: | 1522-1539 0363-6135 |
| DOI: | 10.1152/ajpheart.1978.235.4.h407 |
| Popis: | Rabbit sinoatrial nodes were isolated and studied in an attempt to determine the cell of origin of the true pacemaker potential. Cells of the sinoatrial node of the rabbit giving rise to the characteristic true pacemaker potential were iontophoretically tagged with lanthanum. The lanthanum appeared within the cytoplasm of cells, which morpholigically are (P) cells. The lanthanum appeared as small, amorphous, electron-dense globules. It is concluded from this study that the P or pale cell is the source of the true pacemaker action potential of the sinoatrial node. |
| Databáze: | OpenAIRE |
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