Ferrocenylmethylphosphonate formation. Synthesis, spectroscopy and molecular structure

Autor:	Benjamin R. Horrocks, Nicholas H. Rees, Christian J. Isaac, Andrew Houlton, Mark R. J. Elsegood, William Clegg
Rok vydání:	1998
Předmět:	Phosphoramidite Stereochemistry Medicinal chemistry Phosphonate Inorganic Chemistry Crystal chemistry.chemical_compound chemistry Materials Chemistry Molecule Physical and Theoretical Chemistry Cyclic voltammetry Spectroscopy Derivative (chemistry) Dichloromethane
Zdroj:	ResearcherID Scopus-Elsevier
ISSN:	0277-5387
DOI:	10.1016/s0277-5387(97)00286-6
Popis:	Reaction of ferrocenylmethanol, FcCH2OH, with β-cyano-N,N-diisopropyl chlorophosphoramidite in dichloromethane yields the ferrocenylmethylphosphonate derivative, FcCH2P(O)(N(iPr)2)(OCH2CH2CN), 2a. The crystal and molecular structure of 2a is presented. 31P NMR data suggest that this is formed from FcCH2OP(N(iPr)2)(OCH2CH2CN) via a Michaelis–Arbusov-type rearrangement. Similar behaviour was also observed for 1,2-phenylene chlorophosphite and diethyl chlorophosphite.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e47cd533fddf71aec0a10952b10557d https://doi.org/10.1016/s0277-5387(97)00286-6 Zobrazit plný text záznamu Full Text from ScienceDirect