Correlation of vibratory quantitative sensory testing and nerve conduction studies in patients with diabetes

Autor: Vladimir Skljarevski, John C. Kincaid, Maria C. Jimenez, Karen L. Price
Rok vydání: 2007
Předmět:
Male
Physiology
Neural Conduction
Action Potentials
Audiology
Diabetic Neuropathies
Tibial nerve
Motor Neurons
education.field_of_study
medicine.diagnostic_test
Electrodiagnosis
Middle Aged
medicine.anatomical_structure
symbols
Female
Sensory nerve
Adult
medicine.medical_specialty
Sensory Receptor Cells
Correlation coefficient
Population
Physical examination
Sural nerve
Sensitivity and Specificity
Vibration
behavioral disciplines and activities
Cellular and Molecular Neuroscience
symbols.namesake
Sural Nerve
Predictive Value of Tests
Physiology (medical)
mental disorders
Diabetes Mellitus
Reaction Time
medicine
Humans
Neurons
Afferent
Peripheral Nerves
education
business.industry
Peroneal Nerve
medicine.disease
Pearson product-moment correlation coefficient
Surgery
body regions
Cross-Sectional Studies
Peripheral neuropathy
Neurology (clinical)
Tibial Nerve
business
Zdroj: Muscle & Nerve. 36:821-827
ISSN: 1097-4598
0148-639X
DOI: 10.1002/mus.20880
Popis: Monitoring the course of diabetic peripheral neuropathy (DPN) remains a challenge. Besides clinical examination, nerve conduction studies (NCS) and quantitative sensory testing (QST) are the most commonly used methods for evaluating peripheral nerve function in clinical trials and population studies. In this study the correlation between vibratory QST and NCS was determined. Patients (N = 227) with diabetes mellitus participated in this multicenter, single-visit, cross-sectional study. QST of vibration measured with the CASE IV system was compared with a composite score of peroneal motor and tibial motor NCS and with individual attributes of peroneal, tibial, and sural nerves. The correlation between QST and composite score of NCS was 0.234 (Pearson correlation coefficient, P = 0.001). The correlations between QST and individual attributes of NCS ranged from 0.189 to 0.480 (Pearson correlation coefficients, P < 0.001). The low to moderate correlation between QST and NCS suggests that these tests cannot replace each other but are complementary.
Databáze: OpenAIRE
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