Contribution of high resolution peripheral quantitative CT to the management of bone and joint diseases
Autor: | Nada Ibrahim-Nasser, Eric Lespessailles, Hechmi Toumi, Roland Chapurlat |
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Přispěvatelé: | Imagerie Multimodale Multiéchelle et Modélisation du Tissu Osseux et articulaire (I3MTO), Université d'Orléans (UO) |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
musculoskeletal diseases
0301 basic medicine Male Quality Control medicine.medical_specialty Osteoporosis High resolution 030209 endocrinology & metabolism Osteoarthritis Sensitivity and Specificity Severity of Illness Index 03 medical and health sciences Joint disease 0302 clinical medicine Absorptiometry Photon Rheumatology Bone Density Image Interpretation Computer-Assisted medicine Humans Four-Dimensional Computed Tomography Joint (geology) ComputingMilieux_MISCELLANEOUS Aged Monitoring Physiologic business.industry Middle Aged medicine.disease Peripheral Trabecular bone 030104 developmental biology Cross-Sectional Studies [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system Case-Control Studies Female Radiology Tomography Joint Diseases business Osteoporotic Fractures |
Zdroj: | Joint Bone Spine Joint Bone Spine, Elsevier Masson, 2018, 85 (3), pp.301-306. ⟨10.1016/j.jbspin.2017.04.012⟩ |
ISSN: | 1297-319X |
Popis: | Many imaging modalities have been described to diagnose and monitor osteoporosis (OP), osteoarthritis and inflammatory rheumatic diseases. Over the last ten years, High Resolution peripheral Quantitative Computerized Tomography (HR-pQCT) was shown to be a precise and non invasive technique to study bone and joint diseases in clinical research. It allows the study of both cortical and trabecular bone microarchitecture at the distal tibia and radius, and further applications have been developed such as the study of mechanical properties by the finite element analysis. Thus, in case-control and cross-sectional studies, microarchitecture parameters discriminated fractured individuals independently of areal BMD. Also, microstructure parameters can predict incident fracture in postmenopausal women. In metabolic diseases associated with bone fragility, HR-pQCT may also be used to explore bone changes. In joint disease studies, HR-pQCT was a remarkable tool to assess bone erosion and joint space narrowing at the hand. This article gives an overview of this imaging technique. |
Databáze: | OpenAIRE |
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